Inspector Gadget

Matthew Broderick

John Brown / Inspector Gadget / Robo Gadget

Rupert Everett

Sanford Scolex / Dr. Claw

Joely Fisher

Brenda / Robobrenda

Michelle Trachtenberg

Penny

Andy Dick

Kramer

Cheri Oteri

Mayor Wilson

Mike Hagerty

Sikes

Dabney Coleman

Chief Quimby

D.L. Hughley

Gadgetmobile (voice)

René Auberjonois

Artemus Bradford

Frances Bay

Thelma

Mr. T

Mr. T

Richard Kiel

Famous Big Guy with Silver Teeth

Richard Lee-Sung

Famous Villain with Deadly Hat

Bobby Bell

Famous Identifier of Sea Planes

Hank Barrera

Famous Native American Sidekick