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Michelle Pfeiffer

Melanie Parker

George Clooney

Jack Taylor

Mae Whitman

Maggie Taylor, Jack's daughter

Alex D. Linz

Sammy Parker, Melanie's son

Charles Durning

Lew, Jack's boss

Jon Robin Baitz

Mr. Yates, Jr.

Ellen Greene

Mrs. Elaine Lieberman

Amanda Peet

Celia

Joe Grifasi

Manny Feldstein

Pete Hamill

Frank Burroughs

Anna Maria Horsford

Evelyn

Gregory Jbara

Freddy

Sheila Kelley

Kristen, Jack's ex-wife

Bitty Schram

Marla

Barry Kivel

Mr. Yates, Sr.

Robert Klein

Dr. Martin